反应详情

1.10 g (2.43 mmol) of tert-butyl [6-chloro-3-(4-methoxybenzenesulfonyl)-2-oxo-2,3-dihydrobenzimidazol-1-yl]acetate (XIIg) were dissolved in dichloromethane (40 ml) and, while stirring at room temperature, trifluoroacetic acid (20 ml) was added. The reaction solution was stirred for 2 h and then the solvent and excess trifluoroacetic acid were removed in vacuo. The residue was taken up again in toluene, concentrated in vacuo and then dried in vacuo. Yield: 0.82 g (95%) of white solid

1. stirringThe reaction solution was stirred for 2 h
2. customthe solvent and excess trifluoroacetic acid were removed in vacuo
3. concentrationconcentrated in vacuo
4. customdried in vacuo