Water → HCID 4065164, compound

HRID 1644609Notes

Reaction equation

HRID 1644609 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)[C:5]([OH:7])=[O:6].N1C=CC=C[CH:15]=1.[C:20](OC(=O)C)(=[O:22])[CH3:21].O>C(Cl)Cl>[C:20]([NH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)[C:5]([O:7][CH3:15])=[O:6])(=[O:22])[CH3:21]

Participants

6

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 7918Acetic AnhydrideHCID 2393423-Amino-5-nitrobenzoic acid

Product 1

HCID 4065164HCID 4065164, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

3-Amino-5-nitrobenzoic acid ([23218-93-1], 0.99 g, 5.05 mmol) was stirred in DCM (20 mL) and pyridine (2 mL) at 0° C. Acetic anhydride (1 mL, 10 mmol) was added. The reaction was stirred overnight. Water (30 mL) was added. A precipitate formed and was collected by filtration. [M+H] calc'd for C10H10N2O5 239; found, 239.

Workup

  1. customat 0° C
  2. customA precipitate formed
  3. filtrationwas collected by filtration

Sources & evidence

ORD record
ord-b2e16b753bfc4af88dd9dbe2e38f76cb
Source dataset
uspto-grants-2012_02
Patent number
US08124617B2

Reaction notes

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