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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644613Generated: October 28, 2026

Hydrochloric Acid → HCID 59243016, compound

https://huagongshe.com/reaction/1644613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 58948855HCID 58948855—
SolventMethanolHCID 887—
ProductHCID 59243016HCID 59243016—

Reaction Steps

Methyl 3-(2-fluorobenzyloxy)-5-hydroxybenzoate (224a), 10 mL of Methyl alcohol and 10 mL of 1N NaOH were stirred at ambient temperature for 4 h, acidified with 1N HCl until neutral and extracted into ethyl acetate. The combined organic extracts were dried over magnesium sulfate, filtered and evaporated. The LC/MS gave a calculated and found (M+H+)=263.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124617B2
Source datasetuspto-grants-2012_02
ORD IDord-1cdaf8256b274c8c83e169adb3015e5e
Source noteuspto-grants-2012_02