Hydrochloric Acid → HCID 59243016, compound

HRID 1644613Notes

Reaction equation

HRID 1644613 reaction equation
[F:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[CH2:4][O:5][C:6]1[CH:7]=[C:8]([CH:13]=[C:14]([OH:16])[CH:15]=1)[C:9]([O:11]C)=[O:10].[OH-].[Na+].Cl>CO>[F:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[CH2:4][O:5][C:6]1[CH:7]=[C:8]([CH:13]=[C:14]([OH:16])[CH:15]=1)[C:9]([OH:11])=[O:10]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 58948855HCID 58948855, compound

Product 1

HCID 59243016HCID 59243016, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl 3-(2-fluorobenzyloxy)-5-hydroxybenzoate (224a), 10 mL of Methyl alcohol and 10 mL of 1N NaOH were stirred at ambient temperature for 4 h, acidified with 1N HCl until neutral and extracted into ethyl acetate. The combined organic extracts were dried over magnesium sulfate, filtered and evaporated. The LC/MS gave a calculated and found (M+H+)=263.

Workup

  1. extractionextracted into ethyl acetate
  2. dry with materialThe combined organic extracts were dried over magnesium sulfate
  3. filtrationfiltered
  4. customevaporated
  5. customThe LC/MS gave a calculated and

Sources & evidence

ORD record
ord-1cdaf8256b274c8c83e169adb3015e5e
Source dataset
uspto-grants-2012_02
Patent number
US08124617B2

Reaction notes

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