HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Diaminopyridine → HCID 59243189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Diaminopyridine | HCID 9956 | — |
| Reactant | 3-[(2-Thienylsulfonyl)amino]benzoic acid | HCID 800088 | — |
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59243189 | HCID 59243189 | — |
Reaction Steps
3-(thiophene-2-sulfonamido)benzoic acid (242b) was reacted with 2,3-diaminopyridine, HBTU and TEA in DMF followed by microwave as described previously for example 235. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.74 (s, 1H), 8.45 (d, 1H, J=4.6 Hz), 8.20 (d, 1H, J=7.3 Hz), 8.11 (m, 1H), 7.92 (m, 2H), 7.61 (dd, 1H, J=1.4, 3.7 Hz), 7.52 (t, 2H, J=8.0 Hz), 7.40 (dd, 1H, J=5.0, 7.8 Hz), 7.33 (dd, 1H, J=1.3, 8.0 Hz), 7.12 (dd, 1H, J=3.8, 5.0 Hz); Calc'd for C16H12N4O2S2; (M+H)=357; found 357.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124617B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-5b9bab8019c74547a31fef1b847a5e1c |
| Source note | uspto-grants-2012_02 |