HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → Diisopropylethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Diisopropylethylamine | HCID 81531 | — |
Reaction Steps
Carbamates XX can be obtained through a reaction of compound XVIII with XIX (R′=tert-butyl) in the presence of an amine base such as diisopropylethylamine, triethylamine or pyridine in a suitable inert solvent such as dichloromethane, acetonitrile, 1,4-dioxane, N,N,-dimethylformamide, tetrahydrofuran, or mixtures thereof, at 0° C. to room temperature for several hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124629B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-d1400ad0c0604239a472ef60b478e03f |
| Source note | uspto-grants-2012_02 |