Hydrochloric Acid → Methyl 2-(8-azaspiro[4.5]decan-8-ylsulfonylamino)-4,4-difluoropentanoate
Reaction equation
[CH2:13]1[CH2:14][CH2:15][CH2:16][C:17]12[CH2:18][CH2:19][N:20]([S:23](=[O:24])(=[O:25])[Cl:26])[CH2:21][CH2:22]2.[CH3:27][C:28]#[N:29].[ClH:1].[NH2:2][CH:3]([C:4](=[O:5])[O:6][CH3:7])[CH2:8][C:9]([CH3:10])([F:11])[F:12]>>[NH:2]([CH:3]([C:4](=[O:5])[O:6][CH3:7])[CH2:8][C:9]([CH3:10])([F:11])[F:12])[S:23]([N:20]1[CH2:19][CH2:18][C:17]2([CH2:13][CH2:14][CH2:15][CH2:16]2)[CH2:22][CH2:21]1)(=[O:24])=[O:25]Participants
5
Sources & evidence
- ORD record
- ord-e92f4713a1954e6b863d4f64fcfcbd5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…