Tetrahydrofuran → 4-((1-(benzyloxymethyl)-1H-tetrazol-5-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][n:10]1[n:11][n:12][n:13][cH:14]1.[CH2:20]([CH3:21])[O:22][c:23]1[cH:24][c:25]([O:40][CH:41]([CH3:42])[CH3:43])[c:26]([F:39])[c:27]([CH:28]=[N:29][c:30]2[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]2)[cH:38]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:15][CH2:16][CH2:17][CH2:18][Li:19]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][n:10]1[n:11][n:12][n:13][c:14]1[N:29]([CH2:28][c:27]1[c:26]([F:39])[c:25]([O:40][CH:41]([CH3:42])[CH3:43])[cH:24][c:23]([O:22][CH2:20][CH3:21])[cH:38]1)[c:30]1[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0b9bbe4c8c644271a2f54b0554853ecb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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