Hydrochloric Acid → HCID 11844910, compound

Participants

Reaction Steps

To 6-{[(1-Methyl-1H-imidazole-4-carbonyl)-(3-trifluoromethoxy-benzyl)-amino]-methyl}-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester prepared above (7.74 gm, 15.65 mmol) was added 5 mL of saturated HCl in EtOAc at room temperature. The reaction stirred at room temperature for 4 hours. The mixture was concentrated under reduced pressure to yield 6.63 gm of 1-Methyl-1H-imidazole-4-carboxylic acid (3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-(3-trifluoromethoxy-benzyl)-amide Hydrochloride.

Provenance & Evidence