Potassium Bromide → N,N-bis(1H-benzimidazol-2-ylmethyl)-N-methylamine chromium (III) chloride
Reaction equation
[Cl-:1].[Cr+3:2].N1C2C=CC=CC=2N=C1CNCC1NC2C=CC=CC=2N=1.[Cl-].[Cl-].[NH:26]1[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=2[N:28]=[C:27]1[CH2:35][N:36]([CH2:43][C:44]1[NH:48][C:47]2[CH:49]=[CH:50][CH:51]=[CH:52][C:46]=2[N:45]=1)[CH2:37]CCCCC.[K+].[Br-]>>[Cl-:1].[Cr+3:2].[NH:26]1[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=2[N:28]=[C:27]1[CH2:35][N:36]([CH2:43][C:44]1[NH:45][C:46]2[CH:52]=[CH:51][CH:50]=[CH:49][C:47]=2[N:48]=1)[CH3:37].[Cl-:1].[Cl-:1]Participants
4
Procedure
3b was synthesised by an analogous procedure to that described for 3a using 2e (1 g, 2.8 mmol) and CrCl3(THF)3 (1.05 g, 2.8 mmol). Yield 1.35 g, 93%. Anal. Calc. for C22H27Cl3CrN5 (in %): C, 50.83; H, 5.24; N, 13.47. Found C, 51.05; H, 5.30; N, 13.38. IR (KBr, cm−1), υ 3502 (NH, m), υ 1621-1527 (ArC═C, C═N, m), δ 1498, 1477, 1431 (N—H, s), υ 1273 (CN, m), δ 751 (CH, s). +FAB-MS: (m/z): 483 ([M-Cl]+), 448 ([M-2Cl]).
Sources & evidence
- ORD record
- ord-d0bace07d3d64ee0be13d98d10012e5f
- Source dataset
- uspto-grants-2012_02
- Patent number
- US08124698B2
Reaction notes
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