Hydrochloric Acid → HCID 76849808, compound

Participants

Reaction Steps

A solution of EXAMPLE 74A (1.96 g) in tetrahydrofuran (5 mL) and ethanol (1 mL) was treated with 2N LiOH (5.16 ml), stirred at room temperature for 3 hours and then neutralized to pH 3-4 with 3N HCl. The mixture was extracted with ethyl acetate. The extract was washed (brine), dried (MgSO4) and concentrated to dryness to give the title compound. MS (ESI(+)) m/e 352 (M+H)+.

Provenance & Evidence