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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1645370Generated: October 31, 2026

6,7-Diethoxy-3-methyl-1-benzofuran-2-carboxylic acid → 3-{4-[(6,7-Diethoxy-3-methyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1645370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6,7-Diethoxy-3-methyl-1-benzofuran-2-carboxylic acidHCID 744760—
Reactant3-(4-Amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl esterHCID 66772790—
Product3-{4-[(6,7-Diethoxy-3-methyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl esterHCID 59365186—

Reaction Steps

With a procedure similar to example above, 3-{4-[(6,7-diethoxy-3-methyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester was prepared from 6,7-diethoxy-3-methyl-benzofuran-2-carboxylic acid and 3-(4-amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl ester. LCMS calcd for C27H32N2O7 (m/e) 496, obsd 497 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124766B2
Source datasetuspto-grants-2012_02
ORD IDord-eed3f273e34c42f78c184d9e428e6ad4
Source noteuspto-grants-2012_02