反应详情

4-[(5,6-Dimethoxy-1-indanon-2-ylidene)methyl]pyridine (50 g) in methanol and dichloromethane (1:1) was hydrogenated in presence of palladium on carbon (5 g) and a catalytic quantity of perchloric acid at 0.5 kg pressure and room temperature. The solvents were evaporated under vacuum and the residue was taken in ethyl acetate (500 ml), washed with water (50 ml), brine (50 ml), dried over anhydrous sodium sulphate and evaporated in vacuum to yield the product. Yield: 49 g.

1. customat 0.5 kg pressure and room temperature
2. customThe solvents were evaporated under vacuum
3. washwashed with water (50 ml), brine (50 ml)
4. dry with materialdried over anhydrous sodium sulphate
5. customevaporated in vacuum
6. customto yield the product