Dimethylformamide dimethyl acetal → HCID 66775696, compound

HRID 1645438Notes

Reaction equation

HRID 1645438 reaction equation
[C:1]1([N:7]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:8]2[CH:13]=[CH:12][C:11]([C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:22])[CH3:21])=[CH:16][CH:15]=3)=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CO[CH:31](OC)[N:32]([CH3:34])[CH3:33]>>[C:1]1([N:7]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:8]2[CH:13]=[CH:12][C:11]([C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:22])[CH:21]=[CH:31][N:32]([CH3:34])[CH3:33])=[CH:16][CH:15]=3)=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 54590762HCID 54590762, compound

Product 1

HCID 66775696HCID 66775696, compoundYield 97%

Procedure

1-(4′-Diphenylaminobiphenyl-4-yl)ethanone (1.0 g, 2.75 mmol) was reacted with N,N-dimethylformamide dimethylacetal (1.0 g, 8.25 mmol) for 12 hours at 100° C. Non-reacted N,N-dimethylformamide dimethylacetal was removed using a vacuum pump, and water (50 mL) and dichloromethane (100 mL×2) added. The organic layer was separated, filtered, dried and evaporated to obtain the title compound (1.1 g).

Workup

  1. customNon-reacted N,N-dimethylformamide dimethylacetal was removed
  2. additionadded
  3. customThe organic layer was separated
  4. filtrationfiltered
  5. customdried
  6. customevaporated

Sources & evidence

ORD record
ord-6a3b89f990cd4efd9729917cf878d6b8
Source dataset
uspto-grants-2012_02
Patent number
US08124762B2

Reaction notes

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