Methyl 4-methoxyacetoacetate → 2-(2-(Methoxymethyl)-1,3-dioxan-2-yl)ethanol

HRID 1645593Notes

Reaction equation

HRID 1645593 reaction equation
[CH2:1]([C:4]1([CH2:10][CH2:11][OH:12])[O:9][CH2:8][CH2:7][CH2:6][O:5]1)CC.[CH3:13][O:14]CC(=O)CC(OC)=O>>[CH3:13][O:14][CH2:1][C:4]1([CH2:10][CH2:11][OH:12])[O:5][CH2:6][CH2:7][CH2:8][O:9]1

Participants

3

Reactant 2

HCID 123500Methyl 4-methoxyacetoacetateHCID 597924352-(2-Propyl-1,3-dioxan-2-yl)ethanol

Product 1

HCID 597925492-(2-(Methoxymethyl)-1,3-dioxan-2-yl)ethanolYield 34%

Procedure

The same procedure as in the steps (8a) and (8b) of Example 8 was repeated using methyl 4-methoxyacetoacetate to obtain the title compound (4.5 g, total yield: 34%) as a light yellow oil.

Sources & evidence

ORD record
ord-7913e323612a44639fa31b3d52f20879
Source dataset
uspto-grants-2012_02
Patent number
US08124780B2

Reaction notes

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