反应详情

1.03 g of N-(1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidin-3-yl)phthalimide was dissolved in 50 ml of ethanol, to which 2 ml of hydrazine monohydrate was added and refluxed under heating for 14 hours. The solvent was distilled off and an aqueous diluted solution of sodium hydroxide was added to the residue and extracted with chloroform. After drying with anhydrous magnesium sulfate, the solvent was distilled off, to obtain 0.68 g of the above-captioned compound (yield: 100%).

1. additionwas added
2. temperaturerefluxed
3. temperatureunder heating for 14 hours
4. distillationThe solvent was distilled off
5. additionan aqueous diluted solution of sodium hydroxide was added to the residue
6. extractionextracted with chloroform
7. dry with materialAfter drying with anhydrous magnesium sulfate
8. distillationthe solvent was distilled off