Piperidine → HCID 19390869, compound

HRID 1645858Notes

Reaction equation

F[C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[NH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[N:16]1([C:2]2[CH:15]=[CH:14][C:5]([C:6]([C:8]3[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=3)=[O:7])=[CH:4][CH:3]=2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

Reactant 2

HCID 8082Piperidine

HCID 70230194-(4-Fluorobenzoyl)pyridine

Product 1

HCID 19390869HCID 19390869, compound

Conditions

Temperature: 100 °C

Procedure

A mixture consisting of 4.76 g of 4-(4-fluorobenzoyl)pyridine and 9.8 ml of piperidine was stirred at 100° C. for 24 hours and the reaction mixture was then worked up in the same manner as Example 3 to give 5.3 g of the title compound as a yellow oil.

Sources & evidence

ORD record: ord-7a34b224ab5b46d7ad043d7fa66a2cc2
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05177087

Reaction notes

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