Hydrazine → HCID 18369502, compound

HRID 1645918Notes

Reaction equation

HRID 1645918 reaction equation
[C:1]([C:4]1[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:5]=1[C:6]([N:8](CC)CC)=[O:7])(=O)[CH3:2].[NH2:19]N>O>[CH3:18][O:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:5]2[C:4]=1[C:1]([CH3:2])=[N:19][NH:8][C:6]2=[O:7]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 19802545HCID 19802545, compound

Product 1

HCID 18369502HCID 18369502, compoundYield 64%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 0.37 g (1.48 mmol) of 2-acetyl-3-methoxy-N,N-diethylbenzamide* in 5 ml of water was added 5 ml of anhydrous hydrazine. This was heated at reflux for four hours, cooled and the resulting solid filtered and washed with water to provide 0.18 g (64%) of the desired product; mp 257°-260°.

Workup

  1. temperatureThis was heated
  2. temperatureat reflux for four hours
  3. temperaturecooled
  4. filtrationthe resulting solid filtered
  5. washwashed with water

Sources & evidence

ORD record
ord-adfd26f1ec99423b8fdad216330f23d1
Source dataset
uspto-grants-1993_01
Patent number
US05177075

Reaction notes

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