Pipecolic Acid → HCID 54122708, compound

HRID 1646008Notes

Reaction equation

HRID 1646008 reaction equation
[CH2:1]([N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].[NH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH:14]1C(O)=O>C1(C)C=CC=CC=1>[N:13]12[CH2:18][CH2:17][CH2:16][CH2:15][CH:14]1[CH2:3][CH:2]1[CH:11]2[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:1]1

Participants

4

Reactant 2

HCID 849Pipecolic AcidHCID 11084330Ethyl allyl(2-oxoethyl)carbamate

Product 1

HCID 54122708HCID 54122708, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

17.1 g (0.1 mol) of ethyl N-allyl-N-(2-oxoethyl)-carbamate are heated under reflux overnight with 13 g (0.1 mol) of piperidine-2-carboxylic acid in 200 ml of toluene. The mixture is concentrated and the residue is distilled.

Workup

  1. concentrationThe mixture is concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-6f6dc2b50fac43c6bdaaa678b51c4995
Source dataset
uspto-grants-1993_01
Patent number
US05177210

Reaction notes

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