Potassium Carbonate → HCID 53884937, compound

HRID 1646012Notes

Reaction equation

HRID 1646012 reaction equation
[CH3:1][C:2]1([CH3:18])[S:12][CH2:11][N:10]2[CH:3]1[CH2:4][CH:5]1[CH:9]2[CH2:8][N:7](C(OCC)=O)[CH2:6]1.C(=O)([O-])[O-].[K+].[K+]>O>[CH3:1][C:2]1([CH3:18])[S:12][CH2:11][N:10]2[CH:3]1[CH2:4][CH:5]1[CH:9]2[CH2:8][NH:7][CH2:6]1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 54322387HCID 54322387, compound

Product 1

HCID 53884937HCID 53884937, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

6 g (22.2 mmol) of ethyl 9,9-dimethyl-10-thia-1,4-diazatricyclo[6.3.0.02,6 ]undecane-4-carboxylate are heated under reflux overnight with 12 g of Ba(OH)2.8H2O in 100 ml of water. Potassium carbonate is added, barium carbonate is filtered off with suction and the filtrate is extracted ten times using 100 ml of chloroform each time. The extracts are dried over potassium carbonate and concentrated, and the residue is distilled.

Workup

  1. filtrationbarium carbonate is filtered off with suction
  2. extractionthe filtrate is extracted ten times
  3. dry with materialThe extracts are dried over potassium carbonate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-f69f04febad0401fb31546a59b4a27cb
Source dataset
uspto-grants-1993_01
Patent number
US05177210

Reaction notes

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