1-Benzyl-5-methyloctahydropyrrolo[3,4-b]pyrrole → 5-Methyl-octahydropyrrolo(3,4-b)pyrrole

Participants

Reaction Steps

10.3 g (47.6 mmol) of 2-benzyl-7-methyl-2,7-diazabicyclo[3.3.0] octane in 200 ml of ethanol are hydrogenated at 100° C. and 100 bar on 2.5 g of palladium-active carbon (10% Pd). The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.

Provenance & Evidence