Hydrochloric Acid → HCID 178441740, compound

HRID 1646130Notes

Reaction equation

[CH2:1]([C:5]1[N:6]([CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=2[Cl:39])[C:7](/[CH:19]=[C:20](/[C:27]2[NH:31][N:30]=[N:29][N:28]=2)\[CH2:21][C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)=[C:8]([CH2:10][O:11][Si](C(C)(C)C)(C)C)[N:9]=1)[CH2:2][CH2:3][CH3:4].Cl>>[CH2:1]([C:5]1[N:6]([CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=2[Cl:39])[C:7](/[CH:19]=[C:20](/[C:27]2[NH:31][N:30]=[N:29][N:28]=2)\[CH2:21][C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)=[C:8]([CH2:10][OH:11])[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 178441778HCID 178441778, compound

Product 1

HCID 178441740HCID 178441740, compound

Procedure

The title compound is prepared by reacting (E)-1-[2-n-butyl-1-{(2-chlorophenyl)methyl}-4-(t-butyldimethylsilyoxy)methyl-1H-imidazol-5-yl)-2-(1H-tetrazol-5-yl]-3-(2-thienyl)-1-propene with dilute hydrochloric acid.

Sources & evidence

ORD record: ord-48ba77e8d0e04f33878a15ab84c9f65d
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05177096

Reaction notes

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