Boron tribromide → HCID 178441609, compound

HRID 1646136Notes

Reaction equation

HRID 1646136 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:33])[C:7](/[CH:10]=[C:11](/[C:21]2[NH:25][N:24]=[N:23][N:22]=2)\[CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19]C)=[CH:15][CH:14]=2)=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4].B(Br)(Br)Br>C(Cl)Cl>[CH2:1]([C:5]1[N:6]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:33])[C:7](/[CH:10]=[C:11](/[C:21]2[NH:25][N:24]=[N:23][N:22]=2)\[CH2:12][C:13]2[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=2)=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 178441610HCID 178441610, compound

Product 1

HCID 178441609HCID 178441609, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared by reacting (E)-1-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(1H-tetrazol-5-yl)-3-(4-methoxyphenyl)-1-propene with boron tribromide in methylene chloride at room temperature. The product was isolated as the hydrobromide salt; mp 218°-221° C.

Workup

  1. customat room temperature

Sources & evidence

ORD record
ord-0661a1282182449c9cdee7c6720a8498
Source dataset
uspto-grants-1993_01
Patent number
US05177096

Reaction notes

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