4-Amino-6-methyl-2,5-dihydro-1,2,4-triazin-3-one → HCID 54162271, compound

Participants

Reaction Steps

To a solution of 0.5 g (4 mmol) of 2,3,4,5-tetrahydro-3-oxo-4-amino-6-methyl-1,2,4-triazine in 250 ml of ethanol are added, at room temperature, 0.48 g (4 mmol) of 2-methylpyridine-3-carbaldehyde and 1 drop of concentrated HCl. The reaction mixture is stirred for 1/2 hour and then filtered. The isolated solid is washed with ether and dried, affording the title compound of formula ##STR26## in the form of a colourless solid; m.p. 226°-229° C. (yield: 0.6 g; 64%).

Provenance & Evidence