Dimethylformamide dimethyl acetal → HCID 14473602, compound

Participants

Reaction Steps

A mixture of 26 g of 5-aminomethyl-3-ethyl-1,2,4-oxadiazole and 30 ml of dimethylformamide dimethylacetal is heated for 6 1/2 hours to 80° C. (bath temperature). Subsequently, 16 ml of methanol is removed by distillation and the resultant product is purified by bulb tube distillation, thus obtaining 27.9 g (74.8%) of an oil having a boiling point of 130-150° C. (0.05 torr); nD20 :1.4924.

Provenance & Evidence