Acetic Anhydride → HCID 136058307, compound

Participants

Reaction Steps

To a mixture of 5.0 g of S-methyl-N-nitroisothiourea and 25 ml of pyridine was dropwise added 11.3 of acetic anhydride at room temperature over 10 min. After completion of the addition the mixture was stirred at room temperature for 5 hours, and the reaction mixture concentrated. The residue was poured onto 50 ml of 2N hydrochloric acid, and crystals then formed collected by filtration and dried. There was obtained 5.1 g of N-acetyl-S-methyl-N'-nitroisothiourea as white crystals, mp 109°-110° C.

Provenance & Evidence