HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10375132, compound → HCID 10465095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10375132 | HCID 10375132 | — |
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Product | HCID 10465095 | HCID 10465095 | 99.8% |
Reaction Steps
A mixture of 2-(indol-2-yl)-2-methylpropiononitrile (300 mg) and 5% rhodium on alumina powder (500 mg) in 10N-ammonia-methanol was hydrogenated at 50-60 psi for 8 hours. After filtration of the catalyst, the filtrate was evaporated in vacuo to give 2-(indol-2-yl)-2-methylpropylamine (306 mg) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05180728 |
| Source dataset | uspto-grants-1993_01 |
| ORD ID | ord-94bf6d25f65f409a89d6d2424220786e |
| Source note | uspto-grants-1993_01 |