Ethanesulfonyl chloride → HCID 60650381, compound

HRID 1646893Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][C:4]([O:6][CH3:7])=[O:5].[CH2:8]([S:10](Cl)(=[O:12])=[O:11])[CH3:9]>>[CH2:8]([S:10]([NH:1][CH2:2][CH2:3][C:4]([O:6][CH3:7])=[O:5])(=[O:12])=[O:11])[CH3:9]

Participants

Reactant 2

HCID 11667Ethanesulfonyl chloride

HCID 192794Methyl beta-alanate

Product 1

HCID 60650381HCID 60650381, compound

Procedure

N-(ethylsulfonyl)-β-alanine, methyl ester (21) was prepared from methyl β-alaninate and ethanesulfonyl chloride on a 32 mmol scale in the manner described in Example 13 above to yield 1.53 g (24%) of product. Analysis calculated for C6H13NO4S 0.25 H2O (M.W. 199.74): C, 36.08; H, 6.81; N, 7.01; S, 16.05. Found: C, 36.03; H, 6.82; N, 6.97; S, 15.59.

Sources & evidence

ORD record: ord-f78f871432fb449981128376b60a2afe
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05182272

Reaction notes

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