2-Aminobenzaldehyde → HCID 10005431, compound

HRID 1646995Notes

Reaction equation

HRID 1646995 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[S:10]([O:20][C:21]1[CH:26]=[CH:25][C:24]([S:27]([CH2:30][C:31](=O)[CH:32]([CH3:34])[CH3:33])(=[O:29])=[O:28])=[CH:23][CH:22]=1)([C:13]1[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=1)(=[O:12])=[O:11]>C(OCC)C>[CH:32]([C:31]1[C:30]([S:27]([C:24]2[CH:25]=[CH:26][C:21]([O:20][S:10]([C:13]3[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=3)(=[O:12])=[O:11])=[CH:22][CH:23]=2)(=[O:28])=[O:29])=[CH:4][C:3]2[C:2](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:1]=1)([CH3:34])[CH3:33]

Participants

4

Reactant 2

HCID 682552-AminobenzaldehydeHCID 14771497HCID 14771497, compound

Product 1

HCID 10005431HCID 10005431, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
185 °C

Procedure

In a sealed tube a mixture of 0.02 mol of 2-aminobenzaldehyde and 0.02 mol of 1-(4-tosyloxybenzenesulphonyl)-3-methyl-butan-2-one was heated at 185° C. for 2 hours. The mixture was then taken up in dry ethyl ether and filtered. M.P. of the hydrochloride: about 90° C.

Workup

  1. filtrationfiltered
  2. customabout 90° C.

Sources & evidence

ORD record
ord-0b770be041e14966b9d2dceafcdcbde7
Source dataset
uspto-grants-1993_01
Patent number
US05182291

Reaction notes

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