Methoxyisopropylamine → HCID 19926866, compound

HRID 1647278Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:21])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11](OS(O)(=O)=O)[CH:10]=[CH:9][C:8]=2[F:20])(=[O:3])[CH3:2].[CH3:22][O:23][CH2:24][CH:25]([NH2:27])[CH3:26]>>[C:1]([C:4]1[C:5](=[O:21])[NH:6][C:7]2[C:12]([C:13]=1[NH:27][CH:25]([CH3:26])[CH2:24][O:23][CH3:22])=[CH:11][CH:10]=[CH:9][C:8]=2[F:20])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 123458Methoxyisopropylamine

HCID 19926897HCID 19926897, compound

Product 1

HCID 19926866HCID 19926866, compoundYield 87%

Procedure

3-Acetyl-8-fluoro-4-methylsulfoxy-2-quinolinone (2.67g, 0.01 mol) and 1-methoxy-2-propylamine(0.88g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (2.53g, yield: 87%).

Sources & evidence

ORD record: ord-3e1a9d41ea074c4da308493443065b75
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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