2-Methylcyclohexylamine → HCID 23221942, compound

HRID 1647280Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:21])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11](OS(O)(=O)=O)[CH:10]=[CH:9][C:8]=2[F:20])(=[O:3])[CH3:2].[CH3:22][CH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]1[NH2:29]>>[C:1]([C:4]1[C:5](=[O:21])[NH:6][C:7]2[C:12]([C:13]=1[NH:29][CH:24]1[CH2:25][CH2:26][CH2:27][CH2:28][CH:23]1[CH3:22])=[CH:11][CH:10]=[CH:9][C:8]=2[F:20])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 234322-Methylcyclohexylamine

HCID 19926897HCID 19926897, compound

Product 1

HCID 23221942HCID 23221942, compoundYield 66.4%

Procedure

3-Acetyl-8-fiuoro-4-methylsulfoxy-2-quinolinone (2.67g, 0.01 mol) and 2methylcyclohexylamine(1.13g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (2.1g, yield: 66%).

Sources & evidence

ORD record: ord-a63161fbe88d4805811961756dccb6c3
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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