Isoamylamine → HCID 19926927, compound

HRID 1647287Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:22])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11](OS(O)(=O)=O)[C:10]([F:20])=[CH:9][C:8]=2[Cl:21])(=[O:3])[CH3:2].[CH2:23]([NH2:28])[CH2:24][CH:25]([CH3:27])[CH3:26]>>[C:1]([C:4]1[C:5](=[O:22])[NH:6][C:7]2[C:12]([C:13]=1[NH:28][CH2:23][CH2:24][CH:25]([CH3:27])[CH3:26])=[CH:11][C:10]([F:20])=[CH:9][C:8]=2[Cl:21])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 7894Isoamylamine

HCID 19926925HCID 19926925, compound

Product 1

HCID 19926927HCID 19926927, compoundYield 86%

Procedure

3-Acetyl-8-chloro-6-fluoro-4-methylsulfoxy-2-quinolinone (3.02g, 0.01 mol) and isoamylamine (0.87g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (2.79g, yield: 86% ).

Sources & evidence

ORD record: ord-578e10fd77e34f62afa0f9e1057f61aa
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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