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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 164734Generated: October 30, 2026

Tetrahydrofuran → 2-anilino-6-fluoro-7-(hydroxymethyl)-1-phenyl-1,8-naphthyridin-4(1H)-one

https://huagongshe.com/reaction/164734

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
ReactantEthyl 7-anilino-3-fluoro-5-oxo-8-phenyl-5,8-dihydro-1,8-naphthyridine-2-carboxylateHCID 21948195—
Product2-anilino-6-fluoro-7-(hydroxymethyl)-1-phenyl-1,8-naphthyridin-4(1H)-oneHCID 21948134—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-9ef88c7632e74cd69e0f6ec21d63d567
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)