Boron tribromide → HCID 10377396, compound

Participants

Reaction Steps

3-Butyryl-4-chloro-8-methoxyquinoline (26.3 g, 0.1 mol) in dichloromethane (250 ml) was cooled to -78° under nitrogen, and boron tribromide (75 g, 0.3 mol) added slowly. The solution was stirred overnight, warming gradually to room temperature, then quenched with water. The organic solution was separated and evaporated to give the crude product, which was used immediately without further purification.

Provenance & Evidence