HCID 178450495, compound → HCID 10337874, compound

Participants

Reaction Steps

Ethyl-2-butyryl-3-(3-benzoyloxymethylphenylamino)-acrylate (34.37 g, 86.9 mmol) was added portionwise to refluxing diphenyl ether (300 ml) then heated at reflux for 1 hour. After cooling, petroleum ether (b.p. 40°-60°) was added, and the precipitated solid filtered off. Purification by column chromatography (silica, methanol-chloroform) gave the title compound as a solid (10.52 g) m.p. 228°-31°, from dichloromethane.

Provenance & Evidence