Hydrochloric Acid → HCID 19925672, compound

Participants

Reaction Steps

2-[1-Hydroxy-2-(4-hydroxymethylphenoxy)ethyl]-5-isopropylbenzofuran (10 g) obtained in Example 6 was dissolved in 100 ml of pyridine, the mixture was stirred at room temperature for 24 hours with 10 ml of acetic anhydride, poured into ice water, the mixture was acidified with concentrated hydrochloric acid and the crystals separated out therefrom were filtered, dried and recrystallized from ethyl acetate/n-hexane to give 8.2 g of crystals. M.p. 135°-137° C.

Provenance & Evidence