Benzaldehyde → Ethanol, 2-[(1-methylethyl)(phenylmethyl)amino]-

Participants

Reaction Steps

The present invention also relates to a process for preparing α-[2-[acetyl(1-methylethyl)amino]ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide which has the following formula: ##STR11## and comprises the steps of: (a) alkylating 2-aminoethanol using benzaldehyde and ethanol in the presence of a platinum catalyst and hydrogen followed by reductive alkylation using acetone in the presence of a platinum catalyst and hydrogen to give 2-[(1-methylethyl)(phenylmethyl) amino]ethanol;

Provenance & Evidence