Hydrochloric Acid → HCID 86747021, compound

HRID 1647594Notes

Reaction equation

HRID 1647594 reaction equation
[CH3:1][C:2]1[N:3]([C:7]2[CH:8]=[C:9]([C:13]3[CH:18]=[C:17]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:16]=[CH:15][C:14]=3[CH2:34][C:35]([NH2:37])=[O:36])[CH:10]=[CH:11][CH:12]=2)[CH:4]=[CH:5][N:6]=1.[ClH:38]>CCOCC>[ClH:38].[CH3:1][C:2]1[N:3]([C:7]2[CH:8]=[C:9]([C:13]3[CH:18]=[C:17]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:16]=[CH:15][C:14]=3[CH2:34][C:35]([NH2:37])=[O:36])[CH:10]=[CH:11][CH:12]=2)[CH:4]=[CH:5][N:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86747022HCID 86747022, compound

Product 1

HCID 86747021HCID 86747021, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a solution of 500 mg of N-[3-(2-methyl-1H-imidazol-1-yl)phenyl-4-(tetradecyloxy)benzeneacetamide in a minimum of ether is treated with 70 ml of ether saturated with hydrogen chloride. The resulting solid is collected via centrifugation, washed with ether and vacuum dried to give 0.4 g of the desired product as a white solid, m.p. 175°-178° C.

Workup

  1. customThe resulting solid is collected via centrifugation
  2. washwashed with ether and vacuum
  3. customdried

Sources & evidence

ORD record
ord-c364e3e395b9465881daf6ad3c4c71cf
Source dataset
uspto-grants-1995_07
Patent number
US05432189

Reaction notes

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