HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetaldehyde → Imidazo[1,2-a]pyridine-8-carboxylic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetaldehyde | HCID 33 | — |
| Reactant | 2-Aminonicotinic acid | HCID 72930 | — |
| Product | Imidazo[1,2-a]pyridine-8-carboxylic acid hydrochloride | HCID 11715356 | 88% |
Reaction Steps
Using 2-aminonicotinic acid (14.1 g, 0.102 mol) and chloroacetaldehyde [45% aqueous solution (8.6 g, 0.11 mol)], the same procedure as described above in example C was used. After workup 17.5 g (88%) of the title compound, m.p. 299°-300° C. (decomp), was isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05434161 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-1f80b50eab3c45f4860afde8e98ccad0 |
| Source note | uspto-grants-1995_07 |