Phosphorus trichloride → HCID 10520185, compound

HRID 1647725Notes

Reaction equation

[N:1]12[CH2:8][CH2:7][CH2:6][C:5]1([CH2:9][CH2:10][NH:11][C:12]1[CH:13]=[N+:14]([O-])[C:15]3[C:20]([C:21]=1[N+:22]([O-:24])=[O:23])=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:4][CH2:3][CH2:2]2.P(Cl)(Cl)Cl>>[N:1]12[CH2:8][CH2:7][CH2:6][C:5]1([CH2:9][CH2:10][NH:11][C:12]1[CH:13]=[N:14][C:15]3[C:20]([C:21]=1[N+:22]([O-:24])=[O:23])=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:4][CH2:3][CH2:2]2

Participants

Reactant 2

HCID 24387Phosphorus trichloride

HCID 10641049HCID 10641049, compound

Product 1

HCID 10520185HCID 10520185, compoundYield 66.3%

Procedure

3-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]amino- 4-nitroquinoline 1-oxide and phosphorus trichloride were reacted in the same manner as in Example 6 to obtain the titled compound in a yield of 66.3%.

Sources & evidence

ORD record: ord-85d224e678a2468d9061355744f36cc1
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05434165

Reaction notes

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