Hydrochloric Acid → Venom

HRID 1647846Notes

Reaction equation

HRID 1647846 reaction equation
[O:1]1[CH2:5][CH2:4][CH:3]([CH2:6][N:7]2CN(C)[CH2:10][N:9](C)[C:8]2=[N:15][N+:16]([O-:18])=[O:17])[CH2:2]1.Cl>C(O)C>[O:1]1[CH2:5][CH2:4][CH:3]([CH2:6][NH:7][C:8]([NH:9][CH3:10])=[N:15][N+:16]([O-:18])=[O:17])[CH2:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53824101HCID 53824101, compound

Product 1

HCID 135779803VenomYield 72.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
40 °C

Procedure

A mixture comprising 0.7 g of 1-{(tetrahydro-3-furanyl)methyl}-2-(nitroimino)-3,5-dimethylhexahydro-1,3,5-triazine, 5 ml of 1 N hydrochloric acid and 5 ml of ethanol was stirred at 40° C. for an hour. The reaction fluid was concentrated under a reduced pressure and purified by column chromatography to obtain 0.4 g of 1-{(tetrahydro-3-furanyl)methyl}-2-nitro-3-methylguanidine.

Workup

  1. concentrationThe reaction fluid was concentrated under a reduced pressure
  2. custompurified by column chromatography

Sources & evidence

ORD record
ord-29901af8b638498e94f099fe143d30c1
Source dataset
uspto-grants-1995_07
Patent number
US05434181

Reaction notes

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