Methylamine → HCID 19921108, compound

HRID 1647888Notes

Reaction equation

HRID 1647888 reaction equation
[C:1]([CH2:4][CH2:5][NH:6][C:7]([C:9]1[CH:36]=[CH:35][C:12]2[N:13]([CH3:34])[C:14]([CH:16]3[CH2:21][CH2:20][CH:19]([CH2:22][N:23]4C(=O)C5=CC=CC=C5C4=O)[CH2:18][CH2:17]3)=[N:15][C:11]=2[CH:10]=1)=[O:8])([OH:3])=[O:2].CN>>[NH2:23][CH2:22][CH:19]1[CH2:18][CH2:17][CH:16]([C:14]2[N:13]([CH3:34])[C:12]3[CH:35]=[CH:36][C:9]([C:7]([NH:6][CH2:5][CH2:4][C:1]([OH:3])=[O:2])=[O:8])=[CH:10][C:11]=3[N:15]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 19921527HCID 19921527, compound

Product 1

HCID 19921108HCID 19921108, compound

Procedure

Prepared from 5-[(2-carboxy-ethyl)-aminocarbonyl]-1-methyl- 2-(4-phthalimidomethyl-cyclohexyl)-benzimidazole by treating for 20 hours with 40% aqueous methylamine solution at ambient temperature.

Sources & evidence

ORD record
ord-d978d08acffa4d1cb2b0c7138360fb33
Source dataset
uspto-grants-1995_07
Patent number
US05434150

Reaction notes

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