HCID 15405502, compound → HCID 19918960, compound

HRID 1648193Notes

Reaction equation

HRID 1648193 reaction equation
[CH2:1]([C:3]1[O:8][C:7](C)(C)O[C:5](=[O:11])[C:4]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2].C=[N:19][C:20]([CH3:28])([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH3:21]>C1(C)C(C)=CC=CC=1>[CH2:1]([C:3]1[O:8][CH2:7][N:19]([C:20]([CH3:28])([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH3:21])[C:5](=[O:11])[C:4]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2]

Participants

4

Reactant 2

HCID 15405502HCID 15405502, compoundHCID 19918947HCID 19918947, compound

Product 1

HCID 19918960HCID 19918960, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

Xylene (2 ml) was added to a mixture of 6-ethyl-5-phenyl-2,2-dimethyl-2H,4H-1,3-dioxin-4-one (0.70 g) and N-methylene-1-methyl-1-phenylethylamine (0.44 g), and the resulting mixture was heated at reflux for 20 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.72 g).

Workup

  1. temperaturethe resulting mixture was heated
  2. temperatureat reflux for 20 minutes for reaction
  3. customThe reaction mixture was purified by silica gel chromatography

Sources & evidence

ORD record
ord-00f1f5c98df44dc79513ec323ce65dfd
Source dataset
uspto-grants-1995_07
Patent number
US05436224

Reaction notes

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