HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 19918922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Reactant | 3-Bromothiophene | HCID 13383 | — |
| Reactant | HCID 178429252 | HCID 178429252 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 19918922 | HCID 19918922 | — |
Reaction Steps
A mixture of 0.8 g of 2-hydroxy-4-methylquinoline, 1.22 g of 3-bromothiophene, 0.69 g of potassium carbonate and 1.9 g of iodobenzene in 10 mL of DMF is heated to reflux for 16 hours. The reaction is worked up with water and ethyl acetate and the desired product is isolated by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05436134 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-8cb2c1d57682400fb635cb2e43f6fdc2 |
| Source note | uspto-grants-1995_07 |