Ammonia → HCID 19919896, compound

HRID 1648351Notes

Reaction equation

HRID 1648351 reaction equation
Cl.[CH2:2]1[C:13]2=[C:14]3[C:9](=[CH:10][CH:11]=[CH:12]2)[CH:8]=[CH:7][CH:6]=[C:5]3[CH2:4][C:3]1=O.[C-:16]#[N:17].[Na+].[NH3:19]>O.C(OCC)C>[NH2:19][C:3]1([C:16]#[N:17])[CH2:4][C:5]2[C:14]3[C:9]([CH:8]=[CH:7][CH:6]=2)=[CH:10][CH:11]=[CH:12][C:13]=3[CH2:2]1

Participants

7

Reactant 4

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 8929Sodium CyanideHCID 1423361,3-Dihydro-2-phenalenone

Product 1

HCID 19919896HCID 19919896, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3283Diethyl EtherSolvent

Procedure

1 ml of concentrated hydrochloric acid is added dropwise to a vigorously stirred mixture of 13.7 mmol of 1,3-dihydro-2-phenalenone and 40 mmol of sodium cyanide in 60 ml of water and 80 ml of ethyl ether. After one hour of stirring at 20C., and when settling has taken place, the organic phase is separated, washed with water, dried and evaporated. The residue obtained is treated with 20 ml of a methanolic solution of ammonia (3.5M) with stirring for 5 hours at 20C.

Workup

  1. customthe organic phase is separated
  2. washwashed with water
  3. customdried
  4. customevaporated
  5. customThe residue obtained

Sources & evidence

ORD record
ord-6ab4fa6ffcbc4c75b526d10339dd8ab9
Source dataset
uspto-grants-1995_07
Patent number
US05436261

Reaction notes

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