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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1648413Generated: October 28, 2026

1-(1H-indol-3-yl)-2-methylpropan-2-amine → HCID 19919968, compound

https://huagongshe.com/reaction/1648413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(1H-indol-3-yl)-2-methylpropan-2-amineHCID 9353—
Reactant5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamineHCID 13260—
ReactantHCID 19919937HCID 19919937—
ProductHCID 19919968HCID 19919968—

Reaction Steps

Proceeding as in Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2- [5-diphenylmethyloxy-2-(2-methylprop-1-yloxy)phenoxy]ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(1H-indol-3-yl)-1,1-dimethylethyl]amine and then removing the protective group, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl]{2-[5-hydroxy-2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05436264
Source datasetuspto-grants-1995_07
ORD IDord-abc263c9c4e0490c9fe2ae2101905d79
Source noteuspto-grants-1995_07