huagongshe.com
HRID1648479

反应详情

EQUATION

反应方程式

HRID 1648479 的结构方程式

REACTANTS

反应物

2
结构：NCc1ccccc1
HCID7504

Benzylamine

C7H9N

结构：Cc1ccc(S(=O)(=O)OCCO[C@@H]2CN(C(=O)c3ccccc3)C[C@H]2Br)cc1
HCID86748810

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1ccccc1)N1C[C@H]2OCCN(Cc3ccccc3)[C@H]2C1
HCID53682667

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1C
溶剂HCID7237

o-Xylene

C8H10

PROCEDURE

实验过程

124 g (0.265 mol) of trans-1-benzoyl-3-bromo-4-(2-tosyloxyethoxy)-pyrrolidine are heated with 86 g (0.3 mol) of benzylamine in 1.5 l of xylene under reflux overnight. The salts of the benzylamine are filtered off with suction, and the filtrate is concentrated.

WORKUP

后处理

  1. temperatureunder reflux overnight
  2. filtrationThe salts of the benzylamine are filtered off with suction
  3. concentrationthe filtrate is concentrated