Water → HCID 19920124, compound

Participants

Reaction Steps

A solution of 0.25 mol of the compound prepared in Stage A of Example 10 in 200 ml of ether is added dropwise to a suspension, stirred at 0° C., of 0.25 mol of lithium aluminum hydride in 200 ml of ether. When the addition is complete, the reaction medium is allowed to return to room temperature, and is then stirred for 4 hours at this temperature before being hydrolyzed by adding 20 ml of water. The salts are filtered off and washed twice with ether, and the filtrate is dried and concentrated.

Provenance & Evidence