反应详情

To 60 ml of methanol were added 10.0 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 0.1 g of potassium hydroxide and 3.0 g of ethyleneglycol bis(2,3-epoxypropyl)ether and the mixture was refluxed for 8 hours, under stirring. After completion of the reaction, the reaction mixture was cooled and crystals precipitated were washed with methanol and recrystallized from benzene, giving the desired compound as white crystals melting at 213°-215° C. Referential Example 2.

1. temperaturethe mixture was refluxed for 8 hours
2. customAfter completion of the reaction
3. temperaturethe reaction mixture was cooled
4. customcrystals precipitated
5. washwere washed with methanol
6. customrecrystallized from benzene