Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cumene | HCID 7406 | — |
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | HCID 18956697 | HCID 18956697 | 92% |
Reaction Steps
710 parts of chlorobenzene and 160 parts of AlCl3 are initially introduced. A mixture of 120 parts of cumene, 185.6 parts of p-nitrobenzoyl chloride and 410 parts of chlorobenzene is added dropwise in the course of 1 hour at 20° to 25° C., HCl gas being liberated. The mixture is then heated in the course of 1 hour to 60° C. and stirred for 1 hour at 60° C., 1,400 parts of ice are added, the aqueous phase is separated off in a separating funnel and the organic phase is concentrated in vacuo. 247.6 parts of 4-isopropyl-4'-nitrobenzophenone having a melting point of 95° C. are obtained. Yield: 92% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04413144 |
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| Source dataset | uspto-grants-1983_11 |
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| ORD ID | ord-fa23d2dbe4814f44bea560bee61067ce |
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| Source note | uspto-grants-1983_11 |
|---|
